Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency

Eur J Pharmacol. 1987 Oct 27;142(3):483-5. doi: 10.1016/0014-2999(87)90094-x.

Authors

A L Morrow¹, P D Suzdak, S M Paul

Affiliation

¹ Section on Molecular Pharmacology, National Institute of Mental Health, Bethesda, MD 20892.

PMID: 2828079
DOI: 10.1016/0014-2999(87)90094-x

No abstract available

MeSH terms

Animals
Brain / drug effects
Brain / metabolism
Cerebral Cortex / drug effects
Cerebral Cortex / metabolism
Chlorides / metabolism*
In Vitro Techniques
Male
Muscimol / pharmacology
Rats
Rats, Inbred Strains
Receptors, GABA-A / drug effects*
Steroids / pharmacology*
Synaptosomes / drug effects
Synaptosomes / metabolism

Substances

Chlorides
Receptors, GABA-A
Steroids
Muscimol