Reduced thalamic volume observed across different subgroups of autism spectrum disorders

Ryu Tamura; Hideaki Kitamura; Taro Endo; Naoya Hasegawa; Toshiyuki Someya

doi:10.1016/j.pscychresns.2010.07.001

Reduced thalamic volume observed across different subgroups of autism spectrum disorders

Psychiatry Res. 2010 Dec 30;184(3):186-8. doi: 10.1016/j.pscychresns.2010.07.001. Epub 2010 Sep 17.

Authors

Ryu Tamura¹, Hideaki Kitamura, Taro Endo, Naoya Hasegawa, Toshiyuki Someya

Affiliation

¹ Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

PMID: 20850279
DOI: 10.1016/j.pscychresns.2010.07.001

Abstract

We measured the thalamic volumes of 38 subjects with autism spectrum disorders (ASD), including autism, Asperger's disorder, and pervasive developmental disorder not otherwise specified, and 16 matched healthy controls. Thalamic volume in all ASD subgroups was significantly smaller compared with volume in the control subjects.

MeSH terms

Adolescent
Analysis of Variance
Child
Child Development Disorders, Pervasive / classification
Child Development Disorders, Pervasive / pathology*
Female
Humans
Imaging, Three-Dimensional / methods
Intelligence Tests
Magnetic Resonance Imaging / methods
Male
Severity of Illness Index
Thalamus / pathology*
Young Adult