Abstract
In this report, we describe the development of the first anti-mouse H(4) receptor antibody. Utilising this new immunological probe, new evidence is provided for oligomeric mH(4)Rs and the presence of H(4) receptors on a subpopulation of murine motor neurons. This expands the cell types where the H(4) receptor is expressed in the mammalian CNS.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Antibodies, Blocking / pharmacology*
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Antibody Specificity
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Blotting, Western
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Immunohistochemistry
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Mice
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Molecular Sequence Data
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Motor Neurons / metabolism*
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Receptors, G-Protein-Coupled / immunology
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Receptors, G-Protein-Coupled / metabolism*
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Receptors, Histamine / immunology
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Receptors, Histamine / metabolism*
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Receptors, Histamine H4
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Spinal Cord / cytology
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Spinal Cord / metabolism*
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Transfection
Substances
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Antibodies, Blocking
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Hrh4 protein, mouse
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Receptors, G-Protein-Coupled
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Receptors, Histamine
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Receptors, Histamine H4