Benzamide, a poly(ADP-ribose) polymerase inhibitor, is neuroprotective against soman-induced seizure-related brain damage

Ann N Y Acad Sci. 1999:890:330-5. doi: 10.1111/j.1749-6632.1999.tb08010.x.

Authors

H L Meier¹, G P Ballough, J S Forster, M G Filbert

Affiliation

¹ Pharmacology Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland 21010-5400, USA. Henry.Meier@AMEDD.Army.Mil

PMID: 10668438
DOI: 10.1111/j.1749-6632.1999.tb08010.x

No abstract available

MeSH terms

Animals
Benzamides / pharmacology*
Convulsants
Male
Mitogen-Activated Protein Kinase 1 / drug effects*
Mitogen-Activated Protein Kinase 1 / metabolism
Poly(ADP-ribose) Polymerase Inhibitors*
Rats
Rats, Sprague-Dawley
Seizures / chemically induced
Soman
Temporal Lobe / drug effects*
Temporal Lobe / metabolism
Temporal Lobe / pathology

Substances

Benzamides
Convulsants
Poly(ADP-ribose) Polymerase Inhibitors
benzamide
Soman
Mitogen-Activated Protein Kinase 1