Short communicationμ Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality
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Acknowledgements
We thank Dr. D.W. Melton for granting permission to use the HM1 ES cells, professor Lan Bo Chan for his generous help in many essential parts of this work, Drs. Jim Fujimoto and Pasternak for providing samples of morphine metabolites and Dr. Jim Zadina for providing a sample of endomorphin. This work was supported by NIH grants DA00564, DA01583, DA05695, K05-DA70554, and the F&A Stark Fund of the Minnesota Medical Foundation to HHL.
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