Use of gabapentin for postherpetic neuralgia: Results of two randomized, placebo-controlled studies
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2022, NeuromodulationCitation Excerpt :The SF-3621,22 was used to assess the health of patients. The questionnaire, which can be completed in just 6–9 min, assesses nearly all conceptual domains of the substantially longer generic self-administered questionnaires that have been used in other studies.23 The scores for each domain—bodily pain, general health, mental health, physical function, physical role, role-emotional, social function, and vitality—were recorded before treatment and on day 7 and months 1, 3, and 6 after treatment.
Rapid quantification of gabapentin in human plasma by liquid chromatography/tandem mass spectrometry
2006, Journal of Pharmaceutical and Biomedical AnalysisEffect of systemic and intrathecal gabapentin on allodynia in a new rat model of postherpetic neuralgia
2005, Brain ResearchCitation Excerpt :Controlled clinical trials have demonstrated that gabapentin, an anticonvulsant, reduces neuropathic pain in patients and exhibits positive effects on mood and quality of life [1,23]. However, clinical studies on the effect of gabapentin in patients with postherpetic neuralgia have largely focused on the subjective spontaneous pain (i.e., mean daily pain scores) [21,23,25]. In this study, we quantified the effect of gabapentin on allodynia in RTX-treated rats in an attempt to further validate this animal model of postherpetic neuralgia.
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