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(-)-Syringaresinol-4-O-β-D-glucopyranoside from Cortex Albizziae inhibits corticosterone-induced PC12 cell apoptosis and relieves the associated dysfunction
2020, Food and Chemical ToxicologyCitation Excerpt :Second, cytoplasmic density increases, ΔΨm disappears, permeability changes, and Cyt c is released into the cytoplasm with [Ca2+]i overload. Finally, chromosomal DNA is degraded into about 180–200 bp fragments, and the remains of apoptotic cells are degraded into several apoptotic bodies (Lee et al., 1993). It has been reported that the hippocampal tissue of anxiety model rats exhibits significant apoptosis, and reducing the anxiety-like behavior can reduce the occurrence of apoptosis (Karimi et al., 2014).
Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
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2002, Seminars in OncologyCitation Excerpt :Three patients demonstrated an unexpected and unpredictable severe pulmonary toxicity, the etiology of which remains unclear. Recently, a number of studies have demonstrated that apoptosis is an important mechanism by which chemotherapeutic agents kill susceptible cells.70-72 A surprising number of genes have been implicated in the development of resistance to chemotherapy-induced apoptosis.
Role of programmed cell death in development
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