Amino- and carboxyl-terminal heterogeneity of β-amyloid peptides deposited in human brain☆
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This work was supported in part by research grants from the Naito Foundation, the Uehara Foundation, the Tokyo Metropolitan Institute of Gerontology, and the Ministry of Education, Science, and Culture of Japan.
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We thank Drs. Y. Ihara, K. Yanagisawa, and H. Shimada for indispensable support and discussion and Dr. S. Tsubuki for technical assistance. We also thank Dr. D.J. Selkoe and Dr. T. Aoyagi for valuable comments.