Muscarinic receptor subtypes insubtypes in Airways

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Abstract

Subtypes of muscarinic receptor have recently been shown to exist in the airways of several species, including humans. M1 receptors may be present in sympathetic nerves and parasympathetic ganglia. M2 receptors on cholinergic nerves (autoreceptors) and M3 receptors on smooth muscle and mucus glands. Peter Barnes, Philippe Minette and Jenny Maclagan discuss the possible role of these subtypes of receptor and speculate on the future clinical implications of these discoveries.

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