Elsevier

The Lancet

Volume 341, Issue 8837, 9 January 1993, Pages 84-85
The Lancet

SHORT REPORTS
Nitric oxide synthase activities in human myocardium

https://doi.org/10.1016/0140-6736(93)92559-CGet rights and content

Abstract

Myocardial constitutive and inducible nitric oxide (NO) synthase activities were measured in right ventricular tissue from 17 patients with dilated cardiomyopathy (DCM). A significant activity of inducible enzyme was accompanied by a low activity of the constitutive NO synthase. Thus, the myocardium has the capacity to express both NO synthases. NO may have a physiological as well as a pathological role in the human myocardium. Lancet 1993; 341: 84-85.

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