Brief communicationA new device for the rapid measurement of impaired motor function in mice☆,☆☆
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2020, Comprehensive PsychiatryCitation Excerpt :These findings demonstrated that the elevated oxidative stress in the rat model of schizophrenia could be relieved by crocin. Rotarod test is considered a reliable assay for assessing motor skill and learning in rodents [45]. The balance disturbance in the rotarod test has been shown to be a “nondopamine dependent” motor function and can be induced by applications of NMDAR antagonists including MK-801 [46].
Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain
2019, Archives of Oral BiologyAmeliorating effects of berberine on MK-801-induced cognitive and motor impairments in a neonatal rat model of schizophrenia
2019, Neuroscience LettersCitation Excerpt :All drug solutions were dissolved in 0.9% saline. The rotarod, which is composed of an accelerating rotating rod, is an accepted apparatus for evaluating behavioral parameters indicating motor coordination and balance in rats (Hugo Sachs Electronik, Germany) [19]. The experiment began from a minimum speed of 10 revolutions per minute (rpm) to the maximum speed of 60 rpm.
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This research was carried out with animals maintained in animal care facilities fully accredited by the American Association for Accredation of Laboratory Animal Care.
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A preliminary report of this work was presented as a poster demonstration at the Neuroscience Meetings in Toronto, 1976 (Neurosci Abstracts, II: 865, 1976).