Thyrotropin releasing hormone: antagonism of pentobarbital narcosis in the monkey
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Cited by (44)
Neuropharmacodynamic evaluation of the centrally active thyrotropin-releasing hormone analogue [Leu<sup>2</sup>]TRH and its chemical brain-targeting system
2002, Brain ResearchCitation Excerpt :TRH also has been shown to exert a variety of extrahypothalamic effects in animals. The best-documented effect of this neuropeptide is its analeptic action [3,11,12,16,22] mediated by a cholinergic mechanism [14], and a robust effect of TRH on the stimulation of acetylcholine (ACh) synthesis [23] and, therefore, the subsequent increase of the ACh level [9] has also been shown. Cholinergic dysfunction is intimately associated with numerous CNS maladies such as Alzheimer’s disease (AD) [6,33].
Chemosensitivity of serotonergic neurons in the rostral ventral medulla
2001, Respiration PhysiologySynthesis and behavioral evaluation of a chemical brain-targeting system for a thyrotropin-releasing hormone analogue
1998, European Journal of Medicinal ChemistryAn update on the CNS actions of TRH and its analogs
1998, Life Sciences
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