Human auditory evoked potentials. I: Evaluation of componentsPotentiels evoques auditifs chez l'homme. I: Evaluation des composantes

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Abstract

Fifteen distinct components can be identified in the scalp recorded average evoked potential to an abrupt auditory stimulus. The early components (I–VI) occuring in the first 8 msec after a stimulus represent the activation of the cochlea and the auditory nuclei of the brainstem. The middle latency components (No, Po, Na, Pa, Nb) occuring between 8 and 50 msec after the stimulus probably represent activation of both auditory thalamus and cortex but can be seriously contaminated by concurrent scalp muscle reflex potentials. The longer latency components (P1, N1, P2, N2) occuring between 50 and 300 msec after the stimulus are maximally recorded over fronto-central scalp regions and seem to represent widespread activation of frontal cortex.

Résumé

15 composantes distinctes peuvent être identifiées dans le potentiel évoqué moyen parstimulus auditif abrupt, enregistré sur le scalp. Les composantes précoces (I–VI) survenant dans les premiéres 8 msec aprés le stimulus représentent l'activation de la cochlée et des noyaux auditifs du tronc cérébral. Les composantes de latence intermédiaire (No, Po, Na, Pa, Nb) survenant entre 8 et 50 msec aprés le stimulus représentent probablement l'activation du thalamus et du cortex auditif, mais peuvent être sérieusement contaminées pat des potentiels réflexes des muscles du scalp. Les composantes de latence plus longue (P1, N1, P2, N2) survenant entre 50 et 300 msec aprés le stimulus présentent un maximum sur les regions fronto-centrales du scalp et semblent représenter l'activation très śtalée du cortex frontal.

References (58)

  • J.B. Lehtonen et al.

    The use of a non-cephalic reference electrode in recording cerebral evoked potentials in man

    Electroenceph. clin. Neurophysiol.

    (1971)
  • I. Rapin et al.

    Evoked responses to clicks and tones of varying intensity in waking adults

    Electroenceph. clin. Neurophysiol.

    (1966)
  • D.B. Smith et al.

    Nasopharyngeal phase reversal of cerebral evoked potentials and theoretical dipole implications

    Electroenceph. clin. Neurophysiol.

    (1973)
  • H.G. Vaughan et al.

    The sources of auditory evoked responses recorded from the human head

    Electroenceph. clin. Neurophysiol.

    (1970)
  • W.R. Webster

    The effects of repetitive stimulation on auditory evoked potentials

    Electroenceph. clin. Neurophysiol.

    (1971)
  • H. Weinberg et al.

    Intracerebral events in humans related to real and imaginary stimuli

    Electroenceph. clin. Neurophysiol.

    (1970)
  • E.D. Weitzman et al.

    Auditory evoked responses during different stages of sleep in man

    Electroenceph. clin. Neurophysiol.

    (1965)
  • P.D. Williamson et al.

    Somatosensory evoked responses in patients with unilateral cerebral lesions

    Electroenceph. clin. Neurophysiol.

    (1970)
  • R.G. Bickford

    Physiological and clinical studies of microreflexes

    Electroenceph. clin. Neurophysiol.

    (1972)
  • R.G. Bickford et al.

    Nature of average evoked potentials to sound and other stimuli in man

    Ann. N.Y. Acad. Sci.

    (1964)
  • R. Broughton et al.

    Cortex and scalp recorded somatosensory evoked potentials in man

    Electroenceph. clin. Neurophysiol.

    (1968)
  • R.A. Butler

    Effect of changes in stimulus frequency and intensity on habituation of the human vertex potential

    J. acoust. Soc. Amer.

    (1968)
  • G.G. Celesia et al.

    Auditory evoked responses from the exposed human cortex

    Electroenceph. clin. Neurophysiol.

    (1968)
  • D.T.R. Cody et al.

    Averaged evoked myogenic responses in normal man

    Laryngoscope (St. Louis)

    (1969)
  • R.Q. Cracco

    The initial positive potential of the human scalp-recorded somatosensory evoked response

    Electroenceph. clin. Neurophysiol.

    (1972)
  • H. Davis et al.

    Acoustic relations of the human vertex potential

    J. acoust. Soc. Amer.

    (1966)
  • H. Davis et al.

    Electrical reactions of the brain to auditory stimulation during sleep

    J. Neurophysiol.

    (1939)
  • P.A. Davis

    Effects of acoustic stimuli on the waking human brain

    J. Neurophysiol.

    (1939)
  • M.W. Donald

    Parallel specific and non-specific late components in the somatic evoked response

    Electroenceph. clin. Neurophysiol.

    (1972)
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    This investigation was supported by NASA Grant No. 05-009-198, NIH Grant No. USPHS NS 10482-01, the Medical Research Council of Canada, and the Sloan Foundation.

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