Regular ArticleIdentification of 3′-Methoxy-4′-nitroflavone as a Pure Aryl Hydrocarbon (Ah) Receptor Antagonist and Evidence for More Than One Form of the Nuclear Ah Receptor in MCF-7 Human Breast Cancer Cells
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Current basis for discovery and development of aryl hydrocarbon receptor antagonists for experimental and therapeutic use in atherosclerosis
2015, European Journal of PharmacologyWater exposure assessment of aryl hydrocarbon receptor agonists in Three Gorges Reservoir, China using SPMD-based virtual organisms
2014, Science of the Total EnvironmentCitation Excerpt :A mixture of dissolved organic matter in freshwater has been reported to significantly activate the AhR of various or mixtures of HOCs at environmentally relevant concentrations in exposure to H4IIE-luc cells (Bittner et al., 2011). On the other hand, inhibitors of CYP1A1 have also been identified including fluoranthene (Willett et al., 1998), tributyltin (Bruschweiler et al., 1996), aminoanthracene (Watson et al., 1995), substituted flavones (Lu et al., 1995), etc. However, the inhibition effect is not necessarily harmless to organism.
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