TABLE 2

Mean hepatic and intestinal population relative abundance (pmol P450/mg protein) of CYP3A4, CYP2C9, CYP2C19, and CYP2D6 and the mean activity ratio between intestinal microsomes prepared by elution and mucosal scraping




Livera

Intestineb

Mean Enterocyte Activity Ratioc
CYP3A4 155 43 8.1
CYP2C9 73 8.4 4.7
CYP2C19 14 1 21
CYP2D6
8
0.5
4.2