SD-282 reverses bone destruction as evidenced by bone volume, thickness, and separation
Bone Volume/Trabecular Volume | Thickness | Separation | ||
|---|---|---|---|---|
| mm | ||||
| Vehicle | 0.41 ± 0.1 | 0.13 ± 0.3 | 0.27 ± 0.04 | |
| SD292, 90 mg/kg | 0.74 ± 0.05 | 0.22 ± 0.1 | 0.20 ± 0.05 | |
| p value | <0.009 | <0.009 | 0.047 | |