TABLE 2

Effects of RIF on the microsomal metabolism of ATV (1 μM)

Concentrations	2-OH ATV^a	4-OH ATV^a
μM	% control
0	100.0 ± 3.9	100.0 ± 2.4
10	94.5 ± 2.3	101.8 ± 1.2
25	92.4 ± 5.4	99.8 ± 3.9
50	87.5 ± 6.9^*	91.4 ± 5.7
100	76.3 ± 7.6^**	80.3 ± 5.0^*
250	57.1 ± 1.2^***	75.0 ± 1.5^**

^*, P < 0.05, ^**, P < 0.01; ^***, P < 0.001 significantly different from control.
↵ a Each value represents mean ± S.D. (n = 4).