Influence of dosing time on plasma fluvoxamine concentration after fluvoxamine injection at 9:00 AM or 9:00 PM Each value is the mean with S.E. of six to eight observations.
Hours after Drug Injection | Injection Time | Statistical Significance | ||
|---|---|---|---|---|
| 9:00 AM | 9:00 PM | |||
| ng/ml | ||||
| 0.25 | 1557.13 ± 72.95 | 1569.78 ± 105.75 | N.S. | |
| 0.5 | 1181.84 ± 77.79 | 1009.73 ± 119.89 | N.S. | |
| 1 | 930.78 ± 125.92 | 581.45 ± 33.62 | P < 0.05 | |
| 2 | 231.44 ± 73.33 | 153.49 ± 7.86 | N.S. | |
| 4 | 25.95 ± 1.87 | N.D. |
| |
N.D., not detected.