Parameter | Normal Rats | 5/6 Nx Rats |
---|---|---|
Body weight (g) | 339 ± 5 | 307 ± 6* |
Urine volume (ml/day) | 8.89 ± 1.04 | 19.6 ± 0.9* |
BUN (mg/ml) | 15.4 ± 0.5 | 43.1 ± 1.3* |
Serum creatinine (mg/dl) | 0.758 ± 0.024 | 1.89 ± 0.10* |
Creatinine clearance (ml/min/kg) | 2.83 ± 0.09 | 1.58 ± 0.06* |
Proteinuria (μg/min/kg) | 18.3 ± 2.2 | 152 ± 31* |
Endogenous serum HA (μM) | 12.3 ± 2.4 | 135 ± 12* |
↵* p < 0.01, significantly different from the corresponding parameter in normal rats