TABLE 1

Control values Absolute values and variability (indicated by S.D.) as prevailing under control conditions in the various experimental settings (pooled control data).




Mean

S.D.

n
Skeletal muscle homogenates (μmol of NADH converted/g of tissue/min) 31.63 6.76 61
Liver homogenates (μmol of NADH converted/g of tissue/min) 31.15 7.63 52
Isolated mitochondria, glutamate + malate
    State 4 respiration (nmol of O/mg of protein/min) 22.8 5.6 6
    State 3 respiration (nmol of O/mg of protein/min) 88.5 10.1 6
    Respiratory control 3.86 0.41 6
    P/O (mol/mol) 2.20 0.09 6
Isolated mitochondria, succinate + rotenone
    State 4 respiration (nmol of O/mg of protein/min) 56.7 15.6 6
    State 3 respiration (nmol of O/mg of protein/min) 125.2 11.6 6
    Respiratory control 2.24 0.25 6
    P/O (mol/mol) 1.32 0.06 6
Soleus muscle strips, short-term (90 min)
    Lactate release (μmol/g/h) 15.6 2.8 59
    CO2 production from palmitate (nmol/g/h) 67 12 48
    Glucose oxidation (μmol/g/h) 0.51 0.15 48
    Glycogen synthesis (μmol/g/h) 5.52 1.28 48
Soleus muscle strips, long-term (24 h)
    Lactate release (μmol/g/h) 20.3 4.1 76
    CO2 production from palmitate (nmol/g/h) 92 34 58
    Glucose oxidation (μmol/g/h) 1.78 0.54 94
    Glycogen synthesis (μmol/g/h)
2.60
0.70
98