TABLE 5

Effects of menthol cigarette smoking on the urinary recovery of nicotine and metabolites (n = 12)a

Values in parentheses represent 95% CI.




Menthol

Nonmenthol

p Valueb
%
Nicotine 43.3 (33.2-53.5) 32.9 (20.0-45.8) 0.08
Nicotine glucuronide 13.7 (5.8-21.6) 14.8 (6.6-23.0) 0.72
Cotinine 24.5 (20.8-28.2) 29.0 (19.0-39.1) 0.34
Cotinine glucuronide 8.7 (3.9-13.5) 9.8 (4.0-15.7) 0.45
3′-Hydroxycotinine 7.0 (4.1-9.9) 11.1 (4.6-17.5) 0.18
3′-Hydroxycotinine glucuronide
2.7 (1.2-4.2)
4.1 (1.7-6.5)
0.40
  • a Based on excretion of nicotine-d2 and metabolites as a percentage of total recovery in 8-h urine. Data from two subjects were lost due to analytical problems.

  • b Comparison of menthol versus nonmenthol.