TABLE 1

Values used for the simulation Plasma volume (Vp) = blood volume (Vb) × 0.55.


Probes

Dose

V0

kD0

kB

kR

kO
μmol/g g min-1
Carbamoyl-PROXYL 1.50 Vp × 3.0 0.8 0.035 0.030 kR/50
Carboxy-PROXYL 1.50 Vp × 1.0 6.0 0 0.055 0
TEMPO 0.25 Vp × 1.8 0.5 0.035 8.0 kR/50
TEMPOL 1.50 Vp × 1.8 0.5 0.035 4.0 kR/50
TEMPONE 1.00 Vp × 10.0 0.4 0.035 0.75 kR/50
Amino-TEMPO 0.50 Vp × 4.0 0.6 0.035 2.0 kR/50
Carboxy-TEMPO 1.50 Vp × 2.0 0.8 0.01 0.3 kR/50
CAT-1
0.50
Vp × 1.0
6.0
0
0.13
0