TABLE 3
Th0, Th1, and Th2 cells from ovalbumin transgenic mice (DO11)
T cells from ovalbumin-specific T cell receptor transgenic mice (DO11) were isolated and cultured as described under Materials and Methods. Th0 and polarized Th1 and Th2 cells were challenged with 0.3 μM OVA peptide 323-339 in the presence or absence of the inhibitors. The production of the cytokines was determined by immunoassays.