Receptor | Fold-Activation | S.D. |
---|---|---|
FXR | 1.0 | 0.1 |
LXRα | 1.4 | 0.1 |
LXRβ | 1.1 | 0.1 |
RXRα | 1.4 | 0.4 |
RARα | 0.7 | 0.0 |
VDR | 1.0 | 0.0 |
PXR | 7.5* | 1.9 |
TRβ | 1.3 | 0.1 |
TRα | 0.9 | 0.1 |
PPARα | 0.8 | 0.0 |
PPARδ | 1.1 | 0.1 |
PPARγ | 1.0 | 0.0 |
GR | 0.1 | 0.0 |
PR | 37.2* | 5.6 |
AR | 1.1 | 0.9 |
MR | 0.3 | 0.0 |
ERα | 3.4* | 0.3 |
ERβ | 0.9 | 0.0 |
LXR, liver X receptor; RAR, retinoic acid receptor; VDR, vitamin D receptor; GR, glucocorticoid receptor; AR, androgen receptor; MR, mineralocorticoid receptor.
↵* Statistically significant activation of reporter gene activity over vehicle controls (P < 0.05).