TABLE 2

Kinetic analysis of TEA uptake in freshly isolated proximal tubule cells from 21-day diabetic and nondiabetic rats

Each value represents the mean ± from five separate cell isolations. k is slope of the individual diffusion lines.




Vmax

Km

k
nmol / mg protein / min μM ml / mg protein / min
Diabetic 0.64 ± 0.15* 422 ± 61 0.20 ± 0.03
Nondiabetic
1.17 ± 0.04
288 ± 39
0.33 ± 0.08
  • Statistical significance (*) was assessed by a Student's test (p < 0.05).