Modulator  log K_{B}^{a}  log α^{b} 

Gallamine  −5.70 ± 0.04  −1.30 ± 0.12 
(0.05)  
Alcuronium  −6.10 ± 0.07  0.23 ± 0.07 
(1.7)  
C_{7}/3phth  −5.70 ± 0.23  −1.02 ± 0.06 

 (0.1) 
↵ a Logarithm of the equilibrium dissociation constant for the allosteric modulator at the free receptor, determined from a nonequilibrium binding assay using nonlinear regression according to eqs. 6 through 9 under Materials and Methods. Values represent the mean ± standard error of the mean of three experiments conducted in triplicate.
↵ b Logarithm of the cooperativity factor. Antilogarithm (geometric mean) is given in parentheses. All other details as in footnote a.