TABLE 6

Association between CYP2B6 genotypes and phenotype


SNPs

Group

P

Phenotype
Exon 9 (R487C) CF 0.0015 Activity
All F 0.085 Activity
Intron 3 branch site CF 0.030 Protein
All F 0.048a Activity
All F 0.030b Protein
All persons 0.069c Protein
-8207(putative DR2) All persons 0.070d Activity
-2320 (HNF4) All F 0.069e Activity
-750 (HNF1) All F 0.104f Protein
Exon 1 (R22C)
All F
0.059
Activity
  • F, females; C, Caucasian.

  • a CC vs. CT, P = 0.083; CC vs. TT, P = 0.119.

  • b CC vs. CT, P = 0.021.

  • c CC vs. TT, P = 0.040.

  • d CC vs. TT, P = 0.030.

  • e CC vs. TT, P = 0.034.

  • f CC vs. TC, P = 0.091; CC vs. TT, P = 0.098.