TABLE 1

Data obtained during micropuncture of inbred obese male Zucker (ZDF/Gmi, fa/fa) studied at ∼8 months of age after 6 months of no treatment, ACEI, PPARγ alone, or in combination with ACEI




Hct

CA

ΠA

BP

PGC
vol/dl g/dl mm Hg
Untreated 48 ± 1 5.6 ± 0.2 18 ± 1 144 ± 2 55 ± 4
+ ACEI 50 ± 1 5.7 ± 0.3 19 ± 1 120 ± 4* 49 ± 1
+ PPARγ 43 ± 1* 6.1 ± 0.3 21 ± 2 130 ± 5 53 ± 3
+ PPARγ/ACEI
41 ± 1*
6.2 ± 0.1*
21 ± 1
100 ± 8*
52 ± 4
  • ΠA, colloid osmotic pressure of the plasma.

  • * p < 0.05 versus untreated rats.