TABLE 2

Genes down-regulated after 3 h in LPS-stimulated RAW 264.7 macrophages Data are the average of four independent experiments and were analyzed as described under Materials and Methods. Genes shown were decreased ≥2-fold.


Accession No.

Descriptions

Control/LPS

Control/Adenosine + LPS
X57687 LYL gene (clone L6) 7.69 9.09
M26270 Stearoyl-coenzyme A desaturase 2 3.57 5
AJ007360 ORC5-related protein 2.85 3.33
U07159 Acetyl coenzyme A dehydrogenase, medium chain 2.85 2.63
U70674 m-Numb (m-nb) 2.77 2.7
M33988 Mouse histone H2A0.1 gene 2.63 2.63
U23921 Osmotic stress protein 94 (Osp94) 2.63 2.5
U80932 Serine/threonine kinase 6 2.63 2.7
L26320 Flap structure specific endonuclease 1 2.63 2.63
U67187 G protein signaling regulator RGS2 (rgs2) 2.5 2.43
M29260 Mouse histone 1-0 gene 2.5 2.63
AF053959 Putative ras effector Nore 1 2.5 3.7
Z47766 Cyclin F 2.38 2.56
X86000 N-glycan α 2,8-sialyltransferase 2.38 2.94
M58566 TIS11 primary response gene 2.32 3.33
AF074600 LIM domain transcription factor LMO4 2.32 2.32
D90374 APEX nuclease 2.32 2.63
L07508 Golli-mpb 2.27 2.5
V00727 FBJ osteosarcoma oncogene 2.27 2.85
U22262 Apolipoprotein B editing complex 1 2.27 2.56
AF016583 Checkpoint kinase Chk1 (Chk1) 2.22 2.43
L38822 Max interacting protein 1 2.17 2.38
U75680 Histone stem-loop binding protein (SLBP) mRNA 2.08 2.85
X53176 Integrin α 4 (Cd49d) 2.08 2.43
X82786 Antigen identified by monoclonal antibody Ki 67 2.08 2.85
AF100956 Major histocompatibility locus class II region; Fas-binding protein Daxx (DAXX) gene 2.04 1.96
U25691 Helicase, lymphoid-specific 2.04 2.7
AF012923 p53-inducible zinc finger protein (Wig-1) 2.04 2.7
X75316 seb4 2.04 1.92
M97632 γ-Aminobutyric acid transporter protein (GABA transporter) 2.04 2.17
Z48745 ATP-binding cassette 8 2 2.38
AF017085
BAP-135 homolog
2
2.5