TABLE 1

Genes induced after 3 h in LPS-stimulated RAW 264.7 macrophages

Data are the average of four independent experiments and were analyzed as described under Materials and Methods. Genes shown were induced ≥2-fold.


Accession No.

Descriptions

LPS/Control

Adenosine + LPS/LPS
M88242 Glucocortoid-regulated inflammatory prostaglandin G/H synthase 48.10 0.73
M31418 Interferon activated gene 202 21.15 0.80
X87128 p75 TNF receptor 16.62 1.04
J04491 Small inducible cytokine A3 15.64 0.94
D84196 Tumor necrosis factor-α 13.94 0.92
M31419 Interferon activated gene 204 13.86 0.82
X67644 gly96 9.88 0.93
AF099973 schlafen2 9.44 0.90
U53219 GTPase IGTP 8.54 0.87
M12330 Ornithine decarboxylase 8.16 0.98
U23781 Hematopoietic-specific early-response A1-d protein 8.15 0.96
L32838 Interleukin 1 receptor antagonist 7.97 1.01
AB011665 BAZF 7.92 0.82
L09737 GTP cyclohydrolase 1 7.80 1.00
X61800 CCAA/enhancer binding protein (C/EBP), δ 7.47 0.77
U57524 IκBα 7.39 0.91
AF099974 schlafen3 7.27 0.77
U19118 Transcription factor LRG-21 6.25 0.86
AJ007972 GTPI protein 6.24 0.86
L35528 Manganese superoxide dismutase (MnSOD) 5.72 0.81
U23778 Hematopoietic-specific early-response A1-b protein 5.49 0.97
M90551 Intercellular adhesion molecule 4.89 0.81
U06924 Signal transducer and activator of transcription 1 4.81 0.85
J03023 Hemopoietic cell kinase 4.57 0.88
Y14041 CASHα 4.53 0.92
U09507 Cyclin-dependent kinase inhibitor 1A (P21) 4.51 1.08
AB013137 Glutaredoxin 4.47 1.06
AF099977 schlafen4 4.42 0.85
U20159 76-kDa Tyrosine phosphoprotein SLP-76 4.28 0.82
U05265 Glycoprotein 49 B 4.28 0.89
M22998 Solute carrier family 2 (facilitated glucose transporter) 4.26 0.81
L15435 Tumor necrosis factor (ligand) superfamily, member 9 4.21 1.06
U60020 Transporter 1, ABC (ATP binding cassette) 4.13 0.88
U94828 Retinally abundant regulator of G-protein signaling mRGS-r (RGS-r) 4.11 1.17
Y13089 Caspase-11 4.04 0.85
U40930 Oxidative stress-induced protein 3.73 0.90
AJ001616 Myeloid associated differentiation protein 3.73 0.85
AJ249706 Myosin X (myo 10 gene) 3.69 0.94
M57999 Nuclear factor of κ light chain gene enhancer in B-cells 1 3.65 0.91
U16985 Lymphotoxin-β 3.56 0.71
J04103 E26 avian leukemia oncogene 2, 3 domain 3.55 0.88
X66084 CD44 3.53 0.89
L35049 Bcl2-like 3.53 0.68
X80638 RhoC 3.41 1.03
U09928 Protein kinase, interferon inducible double-stranded RNA-dependent 3.37 1.00
U48403 Glycerol kinase 3.37 0.88
AF052506 Double-stranded RNA-specific adenosine deaminase 3.34 0.98
L10244 Spermidine/spermine N1-acetyl transferase 3.26 0.89
K02236 Metallothionein 2 3.12 0.92
M73696 Glvr-1 3.10 0.81
AF002719 Secretory leukoprotease inhibitor gene 3.03 0.96
AJ242778 ABINl (A20-binding inhibitor of NF-κB activation 3.02 0.91
U35374 Purine nucleoside phosphorylase (Np-b) 2.99 1.00
X61399 F52 2.96 0.89
M31312 βFc receptor type II (FCRII) 2.91 0.72
AF020772 importin α Q2 2.83 0.82
Z50159 Sui1 2.82 0.96
S46665 C5a anaphylatoxin receptor = peptidergic G-protein-coupled receptor 2.82 0.94
AF075136 Sin3-associated protein (sap30) 2.81 0.78
M65027 Glycoprotein 49 A 2.80 0.80
Y08460 Degenerative spermatocyte homolog 2.71 0.81
D63902 Zinc finger protein 147 2.67 0.83
U49513 Small inducible cytokine A9 2.57 0.96
U33626 Promyelocytic leukemia 2.54 0.95
D86176 Phosphatidylinositol 4-phosphate 5-kinase type I-α 2.49 0.92
Y17860 Ganglioside-induced differentiation associated protein 10 2.48 0.86
U95498 AF1q 2.47 0.72
X60304 Protein kinase C, δ 2.46 0.85
J04509 Jun proto-oncogene related gene d1 2.38 0.91
X70956 TOP gene for topoisomerase I 2.38 0.83
U77461 Complement component 3a receptor 1 2.34 0.85
U18869 Mitogen-responsive 96-kDa phosphoprotein p96 2.33 0.86
M59821 Growth factor-inducible protein (pip92) 2.31 0.84
L13732 Natural resistance-associated macrophage protein 1 2.29 0.91
D13003
Reticulocalbin
2.29
0.74
AB024427 Sid1669p 2.25 0.81
U68064 Ceroid lipofuscinosis 2.25 0.99
AF038008 Tyrosylprotein sulfotransferase-1 2.23 0.91
AB033887 mACS4 variant2 mRNA for Acyl-CoA synthetase 4 variant 2 2.23 0.78
D13695 Lymphocyte antigen 84 2.20 0.77
AJ009862 Transforming growth factor-β1 2.19 0.92
AF020313 Proline-rich protein 48 2.17 0.80
M34603 Proteoglycan core protein 2.14 1.00
M59446 Scavenger receptor 2.12 0.79
X76850 Mitogen-activated protein kinase-activated protein kinase 2 2.09 0.94
V00756 Interferon-β 2.09 0.81
AF061272 C-type lectin (Mcl)/ 2.07 0.93
X07888 3-Hydroxy-3-methylglutaryl coenzyme A reductase 2.07 0.88
Y15163 mrg1 protein 2.06 0.82
X54056 Proprotein convertase subtilisin/kexin type 3 2.06 0.95
AF033186 WSB-1 mRNA 2.04 0.76
L02526 Protein kinase, mitogen activated, kinase 1, p45 2.02 0.84
D89728 LOK 2.02 0.83
V00835 Metallothionein 1 2.02 0.93
D87691 eRF1 2.01 0.86
M35247 Histocompatibility 2, T region locus 17 2.01 0.93
X84797 Similar to human hematopoietic specific protein 1 2.00 1.02
AB027565
TXNRD1 mRNA for thioredoxin reductase 1
2.00
0.92