Microvessel density in subcutaneous (s.c.) and intracerebral (i.c.) tumors after treatment regimens of either SU5418 or dimethyl sulfoxide vehicle in microdialysis study
| All values are expressed as a percentage and represent the mean ± S.D., n = 6. | ||||||
|---|---|---|---|---|---|---|
| Treatment Group | Region | |||||
| Periphery/s.c. | Stroma/s.c. | Periphery/i.c. | ||||
| Dimethyl sulfoxide vehicle | 37.4 ± 12.7a | 20.0 ± 2.9b | 8.4 ± 3.0a | |||
| SU5416 (25 mg/kg) | 28.3 ± 11.0 | 15.9 ± 3.9 | 7.1 ± 1.8 | |||