Parameter estimates for CDF disposition in livers from wild-type rats in the presence or absence of probenecid
| Rate constant (min−1) | Control | Probenecid (260 μM) |
|---|---|---|
| k 12 | 0.024 ± 0.005 | 0.0023 ± 0.00063-150 |
| k 21 | 0.003 ± 0.004 | 0.007 ± 0.003 |
| k 20 | 0.16 ± 0.05 | 0.083 ± 0.0063-150 |
Values are mean ± S.D., n = 3/group.
↵3-150 p < 0.05, values compared with control.