Table 2

Recovery of CDF in perfusate

Condition	CDF		CDFDA
Condition	5 μM	50 μM	5 μM	50 μM
Control	91 ± 4	92 ± 2	81 ± 2^2-a	72 ± 4^2-a
Probenecid (260 μM)	93 ± 2	88 ± 2	83 ± 4	69 ± 5
Probenecid (4 mM)	91 ± 6	90 ± 6	65 ± 3^2-b	48 ± 2^2-b

Data are expressed as percentage of dose recovered as CDF at the end of the 5-min incubation at physiological temperature and pH. Data reflect CDF recovery from perfusate after CDF or CDFDA dose. Values are mean ± S.D., n = 3/group.

↵2-a p < 0.05, comparison of CDFDA to CDF controls.
↵2-b p < 0.05, values compared with control in relevant group.