Kinetic parameters for the uptake of cerivastatin in cryopreserved human hepatocytes
| Lot No. | Km | Vmax | Vmax/Km | Pdif |
|---|---|---|---|---|
| μM | pmol/min/106cells | μl/min/106 cells | μl/min/106 cells | |
| HH-088 | 18.3 ± 6.9 | 5200 ± 1970 | 284 ± 108 | 70.2 ± 13.9 |
| HH-106 | 2.61 ± 1.48 | 553 ± 161 | 212 ± 62 | 65.1 ± 8.3 |
| HH-117 | 3.72 ± 1.29 | 362 ± 120 | 97.3 ± 32.3 | 41.7 ± 3.4 |