Table 2

Summary of kinetic parameters of DAT in the nucleus accumbens of the rat after 10 days of pretreatment with saline or cocaine and a subsequent 10-day withdrawal period.

r (fmol/mg tissue/day)9391
t 1/2(days)2.22.2

In this table, k is the transporter degradation rate constant, r is the transporter production rate, andt1/2 is the half-life of transporter repopulation. These values were calculated by generating a linear fit of the data shown in Fig. 4.