Table 1

Hemodynamics and LV function in conscious dogs before and after development of pacing-induced heart failure

NPre-Pacing BaselineHeart Failure
Heart rate (bpm)881  ± 4117  ± 51-150
Mean arterial pressure (mm Hg)896  ± 283  ± 21-150
Left atrial pressure (mm Hg)72  ± 123  ± 11-150
LV end-diastolic pressure (mm Hg)85  ± 124  ± 11-150
LV systolic pressure (mm Hg)8119  ± 398  ± 31-150
LV dP/dtmax (mm Hg/s)82893  ± 1121373  ± 571-150
LV dP/dt/40 (s−1)82261  ± 831236  ± 581-150
LV fractional shortening (%)625  ± 1.111  ± 1.21-150
LV stroke work (dyne/cm × 103)6131  ± 844  ± 51-150
LV dP/dtmin (mm Hg/s)82661  ± 831612  ± 611-150
LV relaxation τ (ms)824  ± 1.133  ± 2.11-150

All data are mean ± S.E.

  • 1-150P < 0.05 vs. pre-pacing baseline.