Number of component molecules in VLDL and VLDL diameter of guinea pigs treated with 0.0, 0.8, 3.7, and 13.4 mg/kg/day ASBT inhibitor
Treatment | VLDL Components | ||||
---|---|---|---|---|---|
FC | TG | CE | PL | Diameter (A) | |
mg/kg/day | |||||
ASBT inhibitor | |||||
0.0 (control) | 570 ± 236 | 2161 ± 574 | 239 ± 112 | 414 ± 197 | 327.5 ± 70.9 |
0.8 | 835 ± 332 | 2273 ± 1297 | 474 ± 325 | 461 ± 355 | 278.8 ± 71.6 |
3.7 | 1005 ± 502 | 2225 ± 1154 | 909 ± 883 | 570 ± 382 | 289.3 ± 58.2 |
13.4 | 672 ± 221 | 3715 ± 3885-150 | 387 ± 215 | 703 ± 162 | 433.8 ± 52.95-150 |
Data are presented as means ± S.D.; n = 10/group. Values in the same column with different superscripts are significantly different as determined by one-way ANOVA and the Newman-Keuls as post hoc test.
FC, free cholesterol; CE, cholesteryl ester; PL, phospholipid.
↵5-150 P < 0.05.