Table 2

Food consumption and drug intake per day of guinea pigs treated with 0, 0.8, 3.7, and 13.4 mg/kg/day of ASBT inhibitor

TreatmentFood IntakeASBTBody WtASBT
mg/kg/day g/day mg/day g mg/kg/day
ASBT Inhibitor
0.0 (control)26.2 ± 7.7561 ± 101
  0.823.1 ± 3.70.42 ± 0.072-165 503 ± 470.83 ± 0.082-165
  3.724.8 ± 7.92.23 ± 0.712-165 602 ± 553.71 ± 1.052-165
 13.420.3 ± 2.47.32 ± 0.882-165 547 ± 4013.36 ± 1.102-165

Data are presented as means ± S.D.; n = 6/group. Values in the same column with different superscripts are significantly different as determined by one-way ANOVA and the Newman-Keuls as post hoc test.

  • 2-165P < 0.001.