Effectiveness of anti-TNF therapies in treatment of Crohn's disease in three separate studies
Treatment Group | Infliximab 5 mg/kg | Etanercept 25 mg s.c. | CDP571 10 mg/kg |
---|---|---|---|
Placebo1-a | 4/24 (17%) | 9/20 (45%) | 15/56 (27%) |
Anti-TNF treatment1-a 1-b | 22/27 (81%) | 9/23 (39%) | 29/54 (54%) |
No. to treat | 1.6 | N/A | 3.7 |
Odds ratio (confidence interval) | 20.8 (4.95, 87.4) | 0.78 (0.23, 2.63) | 3.17 (1.43, 7.03) |