Specific [3H]diprenorphine binding
| Intestinal Region | Myenteric Plexus | Submucosal Plexus | ||
|---|---|---|---|---|
| Bmax | KD | Bmax | KD | |
| fmol/mg | nM | fmol/mg | nM | |
| Jejunum | 73.63 (69.35–77.90)1-a | 0.2973 (0.2397–0.3550) | 51.91 (44.90–58.91) | 0.1773 (0.0762–0.2783) |
| Ileum | 54.26 (39.34–69.18) | 0.2178 (−0.009832–0.4454) | 89.01 (47.61–130.4) | 0.4041 (−0.1786–0.9868) |
| Cecum | 77.14 (62.93–91.35) | 0.2639 (0.09736–0.4303) | 67.97 (61.52–74.42) | 0.2103 (0.1364–0.2841) |
| Proximal colon | 147.8 (107.1–188.1) | 0.2801 (0.03237–0.5277) | 95.25 (90.95–99.56) | 0.5487 (0.4791–0.6184) |
| Distal colon | 85.90 (77.40–94.40) | 0.2949 (0.1981–0.3918) | 51.69 (40.90–62.48) | 0.4794 (0.1870–0.7718) |
↵1-a Values represent mean (95% CI) of 4 to 16 replications using membranes obtained from three to nine pigs.