Table 2

Genes induced greater than 2-fold by rifampin as determined by oligonucleotide-based microarray as described in legend of Fig. 2

-Fold InductionGene Name/DescriptionGenBank Accession No.
55.1Cytochrome P450 3A4 X12387
27.7Cytochrome P450 3A7 D00408
12.6Glutathione S-transferase A2 M21758
8.82-a Cytochrome P450 2B6 M29874
6.5Cytochrome P450 2C8 M17397
6.0Human cytochrome P450-IIB M29873
5.0Cytochrome P450 3A5 J04813
4.3Cytochrome P450 4F3 AB002454
3.7Cytochrome P450 2C9 M61855
3.42-a GlutathioneS-transferase A3 AF020919
2.5Cytochrome P450 1B1 U03688
2.3Cytochrome P450 H. sapiens DNA for cyp-related pseudogene X90579
2.1Transthyretin (prealbumin, amyloidosis type I) M10605
2.1Solute carrier family 22 (organic cation transporter), member 5 AF057164

-Fold induction is calculated as the normalized intensity in rifampin treated versus control treated cells.

  • 2-a  Intensity in control treated cells was below level of detection and corrected for as discussed in the text.