Potencies of various compounds in inhibiting 14C-TEA uptake across the basolateral membrane of MDCK cells
| Compounds | IC50 (μM) | n |
|---|---|---|
| Cimetidine | 6.3 ± 0.7 | 1.2 ± 0.2 |
| Decynium-22 | 0.028 ± 0.002 | 1.2 ± 0.08 |
| Testosterone | 2.1 ± 0.4 | 0.82 ± 0.13 |
| Hydrocortisone | 1.9 ± 0.3 | 0.72 ± 0.08 |
| Verapamil | 4.0 ± 0.4 | 0.71 ± 0.05 |
| Dexamethasone | 26 ± 2.2 | 0.48 ± 0.11 |
| Estradiol | 69 ± 28 | 0.28 ± 0.01 |
IC50 and n values were obtained by fitting data from three separate experiments as described under Experimental Procedures and are presented as mean ± S.D.