Table 2

Ki values of unlabeled compounds on the uptake of [14C]salicylate into rOat2-expressed LLC-PK1 cells

InhibitorsKi Values
μM
Indocyanine green1.15  ± 0.18
Ketoprofen1.84  ± 1.84
Glibenclamide12.3  ± 2.1
Diclofenac49.3  ± 10.0
Benzoate86.9  ± 12.7
Verapamil142  ± 59
Ibuprofen155  ± 23
Tolbutamide176  ± 32

Data were taken from Fig. 5. The effects of unlabeled compounds on the uptake of [14C]salicylate into rOat2-expressed cells were examined. These Ki values were determined by nonlinear regression analysis.