Time course of the anxiolytic-like activity of SL651498 (10 mg/kg, p.o.) in the elevated plus-maze test in rats
| % Time Open Arms | % Entries Open Arms | Attempts | |
|---|---|---|---|
| Control | 18 ± 3.1 | 28.7 ± 4.4 | 12 ± 0.5 |
| 0 h 30 min | 39.3 ± 6.53-150 | 56.7 ± 5.73-150 | 5.1 ± 0.93-150 |
| 1 h 30 min | 32.7 ± 3.13-150 | 50.9 ± 2.63-150 | 4.7 ± 0.83-150 |
| 3 h | 34.7 ± 5.33-150 | 49.3 ± 4.13-150 | 5.6 ± 1.33-150 |
| 6 h | 23 ± 4.6 | 39.6 ± 7.4 | 7.4 ± 0.93-150 |
Data represent mean ± S.E.M. n = 7 to 8.
↵3-150 P < 0.05 (Dunnett's ttest).