Table 1

Time for righting reflex recovery (minutes) following GBR 12909 or saline 20 min after ethanol administration

2.5 g/kg Ethanol5 g/kg Ethanol
Saline62.4  ± 15.1 (n = 7)526  ± 56 (n = 4)
10 mg/kg GBR 1290917.3  ± 2.61-a (n = 6)573  ± 39 (n = 3)
20 mg/kg GBR 12909556  ± 12 (n = 3)

Data shown are means ± S.E.M. of time (minutes) to recover righting reflex following administration of GBR 12909 or saline. Voltammetric measurements were not made in these rats.

  • 1-a  Significantly different from saline group, p < 0.05.