Effect of berberine chloride on intestinal ulceration
| Time after Treatment | Diameter of Ulcer | ||
|---|---|---|---|
| TNB Only | TNB + Berberine Chloride (7.5 mg/kg) | TNB + Berberine Chloride (15 mg/kg) | |
| mm | |||
| Day 3 | 3.4 ± 0.6 | 2.9 ± 0.5 | 3.1 ± 0.5 |
| Day 7 | 3.8 ± 0.9 | 3.2 ± 0.6 | 2.5 ± 0.53-a |
Values are mean ± S.D., n = 5. Berberine chloride (15 mg/kg) reduced intestinal ulceration at 1 week compared with TNB (30 mg) group.
↵3-a P < .05, significant difference from TNB control group.