Table 1

A summary of immunohistochemical staining observed for antibodies to BDNF, NGF, bFGF, TGF-β1, and TGF-β2 in tissue from saline and LY379268 (10 mg/kg i.p.)-treated gerbils at 6, 24, 72, and 120 h postinjection

AntibodyTimeTreatment
SalineLY379268 (10 mg/kg i.p.)BCAO (Positive Control)
h
BDNF6
24
72+
120+++
NGF6
24
72+
120++++
bFGF6
24
72++
120+
TGF-β16
24
72+++
120+++
TGF-β26
24
72+++
120+++

The effect of LY379268 on immunohistochemical staining for these neurotrophic factors was examined by light microscopy in the CA1 area of the hippocampus of 6-μm sections using 5-min BCAO as a positive control. Immunostaining product is described on a quantitative scale of −, no staining; +, little staining; ++, moderate staining; +++, intense staining; and ++++, most intense staining.