Table 2

Effect of OA on δ-opioid receptor resensitization

% Inhibition
Control40.8  ± 7
Des13.8  ± 82-150
Res39  ± 6
Res + OA12.4  ± 102-150

Inhibition of 40 μM forskolin-stimulate cAMP accumulation by Eto was determined as described in Materials and Methods in naive cells (control), desensitized cells (Des), and resensitized cells in the absence (Res) or presence of 10 nM OA (Res + OA). Data are mean ± S.D. of three independent experiments realized in triplicate.

  • 2-150P < .05 (ANOVA followed by Bonferroni test).