Pharmacokinetic parameters of EM, DLZ, and VER in rats
| EM | DLZ | VER | |
|---|---|---|---|
| AUC (μg · min/ml) | 1697.8 ± 592.9 | 75.1 ± 8.6 | 109.9 ± 7.8 |
| CLtot(ml/min/kg) | 32.6 ± 13.5 | 67.1 ± 7.4 | 45.7 ± 3.2 |
| t 1/2β (min) | 74.7 ± 22.4 | 52.5 ± 5.7 | 48.8 ± 6.3 |
Values are means ± S.D. (n = 4).