IC50s of inhibition of KATP in porcine artery cells versus β-cells
| Compound | β-Cell | Porcine Coronary Arterial Cell | Ratio (P/β) |
|---|---|---|---|
| μM | mM | ||
| NAT | 7.4 ± 0.2 | 2.3 ± 1.22-a | 311 |
| nM | |||
| GLY | 16.6 ± 0.3 | 46.8 ± 17.8 | 3 (N.S.) |
| REP | 5.0 ± 1.4 | 82.6 ± 14.52-a | 17 |
N.S., not significant.
↵2-a Significantly different from the corresponding values in β-cell.